Most likely not. The story of the Resistance games are pretty easy to follow: evil alien things attack earth, you fight back. A new series of videos on IGN will chronicle some of the behind-the-scenes elements of the game. Today's video, which you can check out after the break, details the franchise's story and how it ties into the upcoming Retribution.
(Also, does anyone else notice the "Rise of the Chimera" title that's in the background? Most likely it's an early name for Retribution, but it would be hilarious if we accidentally discovered a new Resistance game.)