Gamers who played the original will have their memories slightly shattered upon picking up this new version -- characters won't be found in the same spots and new clues, dialogue and gameplay paths will serve to jumble things up.
Another major change is the new "psyche profile," which monitors the player's reactions. Based on these reactions, alterations are made to the game's "visual elements" and the protagonist's actions as he encounters other people and creatures. The psyche profile system sounds interesting, but a bit difficult to fully grasp without seeing in action. Perhaps future gameplay videos will provide better insight into this new feature.