Transcripted takes two seemingly disparate concepts - 2D shooting and match-three puzzle mechanics - and blends them into a single experience. Taken together, these elements tell the story of a scientist working to stop the spread of a nefarious, and strangely intelligent, disease.

The only way to eradicate the disease is to pilot a nano probe to blast rogue cells while simultaneously destroying the pathogen's "pseudo-DNA." The handiest way to do that, as it turns out, is to match up all the pretty colors.